Genetic Transferability of Anomalous Irradiation Alterations of Antibiotic Activity

George E. Bass

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arXiv · 0706.3195

Genetic Transferability of Anomalous Irradiation Alterations of Antibiotic Activity

George E. Bass

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Abstract

It previously has been discovered that visible light irradiation of crystalline substrates can lead to enhancement of subsequent enzymatic reaction rates as sharply peaked oscillatory functions of irradiation time. The particular activating irradiation times can vary with source of a given enzyme and thus, presumably, its molecular structure. The experiments reported here demonstrate that the potential for this anomalous enzyme reaction rate enhancement can be transferred from one bacterial species to another coincident with transfer of the genetic determinant for the relevant enzyme. In particular, the effect of crystal-irradiated chloramphenicol on growth of bacterial strains in which a transferable R-factor DNA plasmid coding for chloramphenicol resistance was or was not present (S. panama R+, E. coli R+, and E. coli R-) was determined. Chloramphenicol samples irradiated 10, 35 and 60 sec produced increased growth rates (diminished inhibition) for the resistant S. panama and E. coli strains, while having no such effect on growth rate of the sensitive E. coli strain. Consistent with past findings, chloramphenicol samples irradiated 5, 30 and 55 sec produced decreased growth rates (increased inhibition) for all three strains.

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George E. Bass. 2007-06-21. Genetic Transferability of Anomalous Irradiation Alterations of Antibiotic Activity. https://arxiv.org/abs/0706.3195

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