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arXiv · 0712.3332

Extreme genetic code optimality from a molecular dynamics calculation of amino acid polar requirement

Thomas Butler·Nigel Goldenfeld·Damien Mathew·Zaida Luthey-Schulten
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Abstract

A molecular dynamics calculation of the amino acid polar requirement is presented and used to score the canonical genetic code. Monte Carlo simulation shows that this computational polar requirement has been optimized by the canonical genetic code more than any previously-known measure. These results strongly support the idea that the genetic code evolved from a communal state of life prior to the root of the modern ribosomal tree of life.

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Thomas Butler, Nigel Goldenfeld, Damien Mathew, Zaida Luthey-Schulten. 2008-04-01. Extreme genetic code optimality from a molecular dynamics calculation of amino acid polar requirement. https://arxiv.org/abs/0712.3332

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