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arXiv · 0803.3086

A Solid-State System for High Temporal Resolution Fluorescence Lifetime Measurements

M. Gersbach·D. L. Boiko·C. Niclass·C. Petersen·E. Charbon
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Abstract

A system for time-correlated single photon counting applications based on CMOS single photon avalanche diodes is presented. An instrument response function of 79 ps allows a fluorescence decay of high-affinity Ca2+ indicator Oregon Green BAPTA-1 to be analyzed with unprecedented temporal resolution in the two-photon excitation regime. A triple exponential decay model is shown to best fit the fluorescence dynamics of OGB-1.

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M. Gersbach, D. L. Boiko, C. Niclass, C. Petersen, E. Charbon. 2008-03-20. A Solid-State System for High Temporal Resolution Fluorescence Lifetime Measurements. https://arxiv.org/abs/0803.3086

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