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arXiv · 0807.0689

Stacks in canonical RNA pseudoknot structures

Hillary S. W. Han·Christian M. Reidys
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Abstract

In this paper we study the distribution of stacks in $k$-noncrossing, $τ$-canonical RNA pseudoknot structures ($ $-structures). An RNA structure is called $k$-noncrossing if it has no more than $k-1$ mutually crossing arcs and $τ$-canonical if each arc is contained in a stack of length at least $τ$. Based on the ordinary generating function of $ $-structures \cite{Reidys:08ma} we derive the bivariate generating function ${\bf T}_{k,τ}(x,u)=\sum_{n \geq 0} \sum_{0\leq t \leq \frac{n}{2}} {\sf T}_{k, τ}^{} (n,t) u^t x^n$, where ${\sf T}_{k,τ}(n,t)$ is the number of $ $-structures having exactly $t$ stacks and study its singularities. We show that for a certain parametrization of the variable $u$, ${\bf T}_{k,τ}(x,u)$ has a unique, dominant singularity. The particular shift of this singularity parametrized by $u$ implies a central limit theorem for the distribution of stack-numbers. Our results are of importance for understanding the ``language'' of minimum-free energy RNA pseudoknot structures, generated by computer folding algorithms.

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BibTeXRIS

Hillary S. W. Han, Christian M. Reidys. 2008-07-04. Stacks in canonical RNA pseudoknot structures. https://arxiv.org/abs/0807.0689

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