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arXiv · 0807.5092

Lipid Flip-Flop Driven Mechanical and Morphological Changes in Model Membranes

Sanoop Ramachandran·P. B. Sunil Kumar·Mohamed Laradji
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Abstract

We study, using dissipative particle dynamics simulations, the effect of active lipid flip-flop on model fluid bilayer membranes. We consider both cases of symmetric as well as asymmetric flip-flops. Symmetric flip-flop leads to a steady state of the membrane with an effective temperature higher than that of the equilibrium membrane and an effective surface tension lower than that of the equilibrium membrane. Asymmetric flip-flop leads to transient conformational changes of the membrane in the form of bud or blister formation, depending on the flip rate.

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Sanoop Ramachandran, P. B. Sunil Kumar, Mohamed Laradji. 2008-08-23. Lipid Flip-Flop Driven Mechanical and Morphological Changes in Model Membranes. https://doi.org/10.1063/1.2981564

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