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arXiv · 0901.1605

Modular organization as a basis for the functional integration/segregation in large-scale brain networks

M. Valencia·M. A. Pastor·MA. Fernandez-Seara·J. Artieda·J. Martinerie·M. Chavez
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Abstract

Modular structure is ubiquitous among real-world networks from related proteins to social groups. Here we analyze the modular organization of brain networks at a large-scale (voxel level) extracted from functional magnetic resonance imaging (fMRI) signals. By using a random walk-based method, we unveil the modularity of brain-webs, and show that modules with a spatial distribution that matches anatomical structures with functional significance. The functional role of each node in the network is studied by analyzing its patterns of inter- and intra-modular connections. Results suggest that the modular architecture constitutes the structural basis for the coexistence of functional integration of distant and specialized brain areas during normal brain activities at rest.

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M. Valencia, M. A. Pastor, MA. Fernandez-Seara, J. Artieda, J. Martinerie, M. Chavez. 2009-04-16. Modular organization as a basis for the functional integration/segregation in large-scale brain networks. https://arxiv.org/abs/0901.1605

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