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arXiv · 0904.2770

ITM Probe: analyzing information flow in protein networks

Aleksandar Stojmirović·Yi-Kuo Yu
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Abstract

Summary: Founded upon diffusion with damping, ITM Probe is an application for modeling information flow in protein interaction networks without prior restriction to the sub-network of interest. Given a context consisting of desired origins and destinations of information, ITM Probe returns the set of most relevant proteins with weights and a graphical representation of the corresponding sub-network. With a click, the user may send the resulting protein list for enrichment analysis to facilitate hypothesis formation or confirmation. Availability: ITM Probe web service and documentation can be found at www.ncbi.nlm.nih.gov/CBBresearch/qmbp/mn/itm_probe

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BibTeXRIS

Aleksandar Stojmirović, Yi-Kuo Yu. 2009-04-17. ITM Probe: analyzing information flow in protein networks. https://doi.org/10.1093/bioinformatics%2Fbtp398

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