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arXiv · 0911.4854

A Process Calculus for Molecular Interaction Maps

Roberto Barbuti·Andrea Maggiolo-Schettini·Paolo Milazzo·Giovanni Pardini·Aureliano Rama
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Abstract

We present the MIM calculus, a modeling formalism with a strong biological basis, which provides biologically-meaningful operators for representing the interaction capabilities of molecular species. The operators of the calculus are inspired by the reaction symbols used in Molecular Interaction Maps (MIMs), a diagrammatic notation used by biologists. Models of the calculus can be easily derived from MIM diagrams, for which an unambiguous and executable interpretation is thus obtained. We give a formal definition of the syntax and semantics of the MIM calculus, and we study properties of the formalism. A case study is also presented to show the use of the calculus for modeling biomolecular networks.

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Roberto Barbuti, Andrea Maggiolo-Schettini, Paolo Milazzo, Giovanni Pardini, Aureliano Rama. 2009-11-25. A Process Calculus for Molecular Interaction Maps. https://doi.org/10.4204/eptcs.11.3

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