Dendritic Actin Filament Nucleation Causes Traveling Waves and Patches

Anders E. Carlsson

doi:10.1103/physrevlett.104.228102

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arXiv · 1005.5314

Dendritic Actin Filament Nucleation Causes Traveling Waves and Patches

Anders E. Carlsson

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Abstract

The polymerization of actin via branching at a cell membrane containing nucleation-promoting factors is simulated using a stochastic-growth methodology. The polymerized-actin distribution displays three types of behavior: a) traveling waves, b) moving patches, and c) random fluctuations. Increasing actin concentration causes a transition from patches to waves. The waves and patches move by a treadmilling mechanism which does not require myosin II. The effects of downregulation of key proteins on actin wave behavior are evaluated.

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Anders E. Carlsson. 2010-05-28. Dendritic Actin Filament Nucleation Causes Traveling Waves and Patches. https://doi.org/10.1103/physrevlett.104.228102

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