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arXiv · 1105.4898

Dynamic simulations of multicomponent lipid membranes over long length and time scales

Brian A. Camley·Frank L. H. Brown
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Abstract

We present a stochastic phase-field model for multicomponent lipid bilayers that explicitly accounts for the quasi-two-dimensional hydrodynamic environment unique to a thin fluid membrane immersed in aqueous solution. Dynamics over a wide range of length scales (from nanometers to microns) for durations up to seconds and longer are readily accessed and provide a direct comparison to fluorescence microscopy measurements in ternary lipid/cholesterol mixtures. Simulations of phase separation kinetics agree with experiment and elucidate the importance of hydrodynamics in the coarsening process.

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Brian A. Camley, Frank L. H. Brown. 2011-05-24. Dynamic simulations of multicomponent lipid membranes over long length and time scales. https://doi.org/10.1103/physrevlett.105.148102

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