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arXiv · 1109.5124

A Branching Process for Virus Survival

J. Theodore Cox·Rinaldo B. Schinazi
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Abstract

Quasispecies theory predicts that there is a critical mutation probability above which a viral population will go extinct. Above this threshold the virus loses the ability to replicate the best adapted genotype, leading to a population composed of low replicating mutants that is eventually doomed. We propose a new branching model that shows that this is not necessarily so. That is, a population composed of ever changing mutants may survive.

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J. Theodore Cox, Rinaldo B. Schinazi. 2011-09-23. A Branching Process for Virus Survival. https://arxiv.org/abs/1109.5124

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