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arXiv · 1112.0186

Recovery of state-specific potential of molecular motor from single-molecule trajectory

Shoichi Toyabe·Hiroshi Ueno·Eiro Muneyuki
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Abstract

We have developed a novel method to evaluate the potential profile of a molecular motor at each chemical state from only the probe's trajectory and applied it to a rotary molecular motor F$_1$-ATPase. By using this method, we could also obtain the information regarding the mechanochemical coupling and energetics. We demonstrate that the position-dependent transition of the chemical states is the key feature for the highly efficient free-energy transduction by F$_1$-ATPase.

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Shoichi Toyabe, Hiroshi Ueno, Eiro Muneyuki. 2011-12-01. Recovery of state-specific potential of molecular motor from single-molecule trajectory. https://doi.org/10.1209/0295-5075%2F97%2F40004

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