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arXiv · 1207.4906

Sources of stochasticity in constitutive and autoregulated gene expression

Rahul Marathe·David Gomez·Stefan Klumpp
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Abstract

Gene expression is inherently noisy as many steps in the read-out of the genetic information are stochastic. To disentangle the effect of different sources of stochasticity in such systems, we consider various models that describe some processes as stochastic and others as deterministic. We review earlier results for unregulated (constitutive) gene expression and present new results for a gene controlled by negative autoregulation with cell growth modeled by linear volume growth.

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Rahul Marathe, David Gomez, Stefan Klumpp. 2012-07-20. Sources of stochasticity in constitutive and autoregulated gene expression. https://doi.org/10.1088/0031-8949%2F2012%2Ft151%2F014068

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