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arXiv · 1208.4271

Minerva and minepy: a C engine for the MINE suite and its R, Python and MATLAB wrappers

Davide Albanese·Michele Filosi·Roberto Visintainer·Samantha Riccadonna·Giuseppe Jurman·Cesare Furlanello
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Abstract

We introduce a novel implementation in ANSI C of the MINE family of algorithms for computing maximal information-based measures of dependence between two variables in large datasets, with the aim of a low memory footprint and ease of integration within bioinformatics pipelines. We provide the libraries minerva (with the R interface) and minepy for Python, MATLAB, Octave and C++. The C solution reduces the large memory requirement of the original Java implementation, has good upscaling properties, and offers a native parallelization for the R interface. Low memory requirements are demonstrated on the MINE benchmarks as well as on large (n=1340) microarray and Illumina GAII RNA-seq transcriptomics datasets. Availability and Implementation: Source code and binaries are freely available for download under GPL3 licence at http://minepy.sourceforge.net for minepy and through the CRAN repository http://cran.r-project.org for the R package minerva. All software is multiplatform (MS Windows, Linux and OSX).

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Davide Albanese, Michele Filosi, Roberto Visintainer, Samantha Riccadonna, Giuseppe Jurman, Cesare Furlanello. 2012-12-10. Minerva and minepy: a C engine for the MINE suite and its R, Python and MATLAB wrappers. https://doi.org/10.1093/bioinformatics%2Fbts707

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