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arXiv · 1209.0505

Focusing in Multiwell Potentials: Applications to Ion Channels

L. Ponzoni·G. L. Celardo·F. Borgonovi·L. Kaplan·A. Kargol
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Abstract

We investigate out of equilibrium stationary distributions induced by a stochastic dichotomous noise on double and multi-well models for ion channels. Ion-channel dynamics is analyzed both through over-damped Langevin equations and master equations. As a consequence of the external stochastic noise, we prove a non trivial focusing effect, namely the probability distribution is concentrated only on one state of the multi-well model. We also show that this focusing effect, which occurs at physiological conditions, cannot be predicted by a simple master equation approach.

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L. Ponzoni, G. L. Celardo, F. Borgonovi, L. Kaplan, A. Kargol. 2012-10-24. Focusing in Multiwell Potentials: Applications to Ion Channels. https://doi.org/10.1103/physreve.87.052137

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