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arXiv · 1210.7164

Vascular networks due to dynamically arrested crystalline ordering of elongated cells

Margriet M. Palm·Roeland M. H. Merks
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Abstract

Recent experimental and theoretical studies suggest that crystallization and glass-like solidification are useful analogies for understanding cell ordering in confluent biological tissues. It remains unexplored how cellular ordering contributes to pattern formation during morphogenesis. With a computational model we show that a system of elongated, cohering biological cells can get dynamically arrested in a network pattern. Our model provides a new explanation for the formation of cellular networks in culture systems that exclude intercellular interaction via chemotaxis or mechanical traction.

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Margriet M. Palm, Roeland M. H. Merks. 2013-06-05. Vascular networks due to dynamically arrested crystalline ordering of elongated cells. https://doi.org/10.1103/physreve.87.012725

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