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arXiv · 1211.7192

Phylogenetic tree reconstruction from genome-scale metabolic models

D. Gamermann·A. Montagud·J. A. Conejero·P. F. de Córdoba·J. F. Urchieguía
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Abstract

A wide range of applications and research has been done with genome-scale metabolic models. In this work we describe a methodology for comparing metabolic networks constructed from genome-scale metabolic models and how to apply this comparison in order to infer evolutionary distances between different organisms. Our methodology allows a quantification of the metabolic differences between different species from a broad range of families and even kingdoms. This quantification is then applied in order to reconstruct phylogenetic trees for sets of various organisms.

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D. Gamermann, A. Montagud, J. A. Conejero, P. F. de Córdoba, J. F. Urchieguía. 2012-11-30. Phylogenetic tree reconstruction from genome-scale metabolic models. https://doi.org/10.1089/cmb.2013.0150

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