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arXiv · 1311.0821

Enzymatic AND Logic Gate with Sigmoid Response Induced by Photochemically Controlled Oxidation of the Output

Vladimir Privman·Brian E. Fratto·Oleksandr Zavalov·Jan Halamek·Evgeny Katz
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Abstract

We report a study of a system which involves an enzymatic cascade realizing an AND logic gate, with an added photochemical processing of the output allowing to make the gate's response sigmoid in both inputs. New functional forms are developed for quantifying the kinetics of such systems, specifically designed to model their response in terms of signal and information processing. These theoretical expressions are tested for the studied system, which also allows us to consider aspects of biochemical information processing such as noise transmission properties and control of timing of the chemical and physical steps.

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Vladimir Privman, Brian E. Fratto, Oleksandr Zavalov, Jan Halamek, Evgeny Katz. 2013-11-04. Enzymatic AND Logic Gate with Sigmoid Response Induced by Photochemically Controlled Oxidation of the Output. https://doi.org/10.1021/jp404054f

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