SearcharxivSearch

arXiv · 1407.0165

Automatic annotation of bioinformatics workflows with biomedical ontologies

Abstract

Legacy scientific workflows, and the services within them, often present scarce and unstructured (i.e. textual) descriptions. This makes it difficult to find, share and reuse them, thus dramatically reducing their value to the community. This paper presents an approach to annotating workflows and their subcomponents with ontology terms, in an attempt to describe these artifacts in a structured way. Despite a dearth of even textual descriptions, we automatically annotated 530 myExperiment bioinformatics-related workflows, including more than 2600 workflow-associated services, with relevant ontological terms. Quantitative evaluation of the Information Content of these terms suggests that, in cases where annotation was possible at all, the annotation quality was comparable to manually curated bioinformatics resources.

Explore related subjects

Keep this discovery

BibTeXRIS

Beatriz García-Jiménez, Mark D. Wilkinson. 2014-07-01. Automatic annotation of bioinformatics workflows with biomedical ontologies. https://arxiv.org/abs/1407.0165

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related papers

UniRec: Cross-stage Multi-Task Fusion with Preference Alignment for Cascaded Recommender Systems

Industrial recommender systems use cascaded stages with different objectives, feature spaces, and latency constraints. Optimizing pre-ranking and ranking separately can create cross-stage inconsistency: upstream models may filter out items preferred by downstream rankers, and independently tuned downstream fusion can offset upstream improvements. Existing multi-task fusion methods focus on multi-objective fusion within the ranking stage, and cross-stage methods typically only add a downstream score factor to upstream ranking. Joint optimization of fusion modules across both stages remains largely unexplored. We propose UniRec, a Unified Cross-stage Recommendation Fusion model. First, the two fusion agents partially share input embeddings and are trained in a single computation graph, so gradients from either stage propagate through the shared representation and influence the other. Second, we introduce a dual-axis preference alignment objective: a vertical cross-stage consistency term transfers downstream pairwise preferences to the upstream fusion score, and a horizontal compact aggregation term reorganizes dozens of pairwise objectives over heterogeneous prior signals into bidirectional preference evidence. Third, we find that unconstrained end-to-end fusion optimization can exploit imbalances in item attribute distributions, over-concentrating on high-reward regions at the cost of other objectives. We therefore add an attribute group-relative regularization that computes advantages within attribute groups and normalizes the policy over the same groups, so uniformly promoting an entire high-reward group yields no optimization gain. Offline, UniRec consistently outperforms single-stage fusion and cross-stage coordination baselines. Online A/B tests show a 0.616\% gain in app usage duration. UniRec is fully deployed on the Kuaishou platform.

cs.IR

VikingRAG: Accurate and Token-efficient Retrieval-augmented Generation over Structured Documents

State-of-the-art retrieval-augmented generation (RAG) methods exploit document structures to acquire sufficient evidence, but often incur substantial token costs. To reduce structural-context tokens without compromising high RAG accuracy, we present {\sf VikingRAG}, a directory-aware semantic data management system that tightly integrates semantic and structural access to support structural-context-efficient, evidence-gap-driven multi-round retrieval. To further reduce token overhead of multi-round interaction, we materialize agentic multi-round retrieval traces as experience edges, and reuse these edges for similar queries, avoiding repeated multi-round exploration. To additionally reduce token costs when agentic multi-round retrieval is unnecessary, we introduce an adaptive escalation strategy that answers from one-round experience-augmented retrieval when the evidence is sufficient, and invokes agentic multi-round retrieval only otherwise. Experiments on real datasets show that the base system {\sf VikingRAG} matches high accuracy of state-of-the-art methods while consuming only 11.6\%--51.9\% of their tokens. With retrieval-trace reuse and adaptive escalation, token costs drop to 5.1\%--32.5\% while maintaining competitive accuracy and practical document-storage performance, showing the utility of this work for emerging AI knowledge bases.

cs.IR

TimelyRAG: Semantic-Temporal Hybrid Retrieval for Time-Critical Question Answering in Overlapping-Evolving Documents

Although large language models (LLMs) and retrieval-augmented generation (RAG) have advanced open-domain question answering (QA), they remain unreliable when documents evolve through amendments. Existing time-sensitive retrieval methods address only the disjoint-evolving environment, where each update is an independent snapshot. However, laws, policies, and regulations often operate in overlapping-evolving environments, where amendments override earlier clauses while preserving most content, creating strong semantic overlap across versions. We propose TimelyRAG, a retriever-agnostic framework that incorporates temporal distance into ranking to align queries with version-appropriate documents. We also introduce TimelyQABench, the first benchmark for regulation-heavy domains with overlapping-evolving challenges. Experiments show consistent gains, up to +28.6% in nDCG@10, highlighting the importance of temporal reasoning for reliable QA over evolving documents. All resources are available at https://github.com/kaist-dmlab/TimelyRAG.

cs.IR