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arXiv · 1411.6167

Fabrication and Characterization of an Amperometric Glucose Sensor on a Flexible Polyimide Substrate

Xiaosong Du·Christopher J. Durgan·David J. Matthews·Joshua R. Motley·Xuebin Tan·Kovit Pholsena·Líney Árnadóttir·Jessica R. Castle·Peter G. Jacobs·Robert S. Cargill·W. Kenneth Ward·John F. Conley Jr.·Gregory S. Herman
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Abstract

This study details the use of printing and other additive processes to fabricate a novel amperometric glucose sensor. The sensor was fabricated using a Au coated 12.7 micron polyimide film as a starting material, where micro-contact printing, electrochemical plating and chloridization, electrohydrodynamic jet (e-jet) printing, and spin coating were used to pattern, deposit, print, and coat functional materials, respectively. We have found that e-jet printing was effective for the deposition and patterning of glucose oxidase inks between ~5 to 1000 micron in width, and we have demonstrated that the enzyme was still active after printing. The thickness of the permselective layer was optimized to obtain a linear response to glucose concentration up to 32 mM. For these sensors no response to acetaminophen, a common interfering compound, was observed.

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Xiaosong Du, Christopher J. Durgan, David J. Matthews, Joshua R. Motley, Xuebin Tan, Kovit Pholsena, Líney Árnadóttir, Jessica R. Castle, Peter G. Jacobs, Robert S. Cargill, W. Kenneth Ward, John F. Conley Jr., Gregory S. Herman. 2014-11-22. Fabrication and Characterization of an Amperometric Glucose Sensor on a Flexible Polyimide Substrate. https://doi.org/10.1149/2.0101504jss

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