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arXiv · 1504.03727

Cavity optomechanical transduction sensing of single molecules

Wenyan Yu·Wei C. Jiang·Qiang Lin·and Tao Lu
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Abstract

We report narrow linewidth optomechanical oscillation of a silica microsphere immersed in a buffer solution. Through a novel optomechanical transduction sensing approach, single 10-nm-radius silica beads and Bovine serum albumin (BSA) protein molecules with a molecular weight of 66 kDalton were detected. This approach predicts the detection of 3.9 kDalton single molecules at a signal-to-noise ration above unity.

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Wenyan Yu, Wei C. Jiang, Qiang Lin, and Tao Lu. 2015-04-14. Cavity optomechanical transduction sensing of single molecules. https://doi.org/10.1038/ncomms12311

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