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arXiv · 1507.03192

Facilitation of polymer looping and giant polymer diffusivity in crowded solutions of active particles

J. Shin·A. G. Cherstvy·W. K. Kim·R. Metzler
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Abstract

We study the dynamics of polymer chains in a bath of self-propelled particles (SPP) by extensive Langevin dynamics simulations in a two dimensional system. Specifically, we analyse the polymer looping properties versus the SPP activity and investigate how the presence of the active particles alters the chain conformational statistics. We find that SPPs tend to extend flexible polymer chains while they rather compactify stiffer semiflexible polymers, in agreement with previous results. Here we show that larger activities of SPPs yield a higher effective temperature of the bath and thus facilitate looping kinetics of a passive polymer chain. We explicitly compute the looping probability and looping time in a wide range of the model parameters. We also analyse the motion of a monomeric tracer particle and the polymer's centre of mass in the presence of the active particles in terms of the time averaged mean squared displacement, revealing a giant diffusivity enhancement for the polymer chain via SPP pooling. Our results are applicable to rationalising the dimensions and looping kinetics of biopolymers at constantly fluctuating and often actively driven conditions inside biological cells or suspensions of active colloidal particles or bacteria cells.

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J. Shin, A. G. Cherstvy, W. K. Kim, R. Metzler. 2015-07-12. Facilitation of polymer looping and giant polymer diffusivity in crowded solutions of active particles. https://doi.org/10.1088/1367-2630/17/11/113008

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