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arXiv · 1608.01279

Theory for the Acoustic Raman Modes of Proteins

Timothy DeWolf·Reuven Gordon
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Abstract

We present a theoretical analysis that associates the resonances of extraordinary acoustic Raman (EAR) spectroscopy [Wheaton et al., Nat Photon 9, 68 (2015)] with the collective modes of proteins. The theory uses the anisotropic elastic network model to find the protein acoustic modes, and calculates Raman intensity by treating the protein as a polarizable ellipsoid. Reasonable agreement is found between EAR spectra and our theory. Protein acoustic modes have been extensively studied theoretically to assess the role they play in protein function; this result suggests EAR as a new experimental tool for studies of protein acoustic modes.

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Timothy DeWolf, Reuven Gordon. 2016-08-03. Theory for the Acoustic Raman Modes of Proteins. https://doi.org/10.1103/physrevlett.117.138101

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