Fast-slow asymptotics for a Markov chain model of fast sodium current

T. Stary; V. N. Biktashev

doi:10.1063/1.5003013

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arXiv · 1703.09418

Fast-slow asymptotics for a Markov chain model of fast sodium current

T. Stary·V. N. Biktashev

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Abstract

We explore the feasibility of using fast-slow asymptotic to eliminate the computational stiffness of the discrete-state, continuous-time deterministic Markov chain models of ionic channels underlying cardiac excitability. We focus on a Markov chain model of the fast sodium current, and investigate its asymptotic behaviour with respect to small parameters identified in different ways.

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BibTeX RIS

T. Stary, V. N. Biktashev. 2017-03-28. Fast-slow asymptotics for a Markov chain model of fast sodium current. https://doi.org/10.1063/1.5003013

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