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arXiv · 1704.06301

Crystallization via tubing microfluidics permits both in situ and ex situ X-ray diffraction

Charline Gerard·Gilles Ferry·Laurent Vuillard·Jean A Boutin·Léonard Chavas·Tiphaine Huet·Nathalie Ferte·Romain Grossier·Nadine Candoni·Stéphane Veesler
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Abstract

We used a microfluidic platform to address the problems of obtaining diffraction quality crystals and crystal handling during transfer to the X-ray diffractometer. We optimize crystallization conditions of a pharmaceutical protein and collect X-ray data both in situ and ex situ.

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Charline Gerard, Gilles Ferry, Laurent Vuillard, Jean A Boutin, Léonard Chavas, Tiphaine Huet, Nathalie Ferte, Romain Grossier, Nadine Candoni, Stéphane Veesler. 2017-03-22. Crystallization via tubing microfluidics permits both in situ and ex situ X-ray diffraction. https://arxiv.org/abs/1704.06301

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