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arXiv · 1705.03994

Theoretical analysis of optoporation efficiency and bubble formation during femtosecond pulse interaction with gold nanoshell

Yevgeniy R. Davletshin·J. Carl Kumaradas
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Abstract

Our group has recently developed a finite element model of a nanoparticle-mediated optical breakdown phenomena. Previously, this model was used to analyze the role of the nanoparticle morphology and the wavelength dependence of a nanoparticle-mediated optical breakdown threshold during near-infrared ps and fs pulse exposures. In this study, we provide a theoretical insight into the optoporation efficiency of live cells and bubble formation threshold during nanoparticle-mediated optical breakdown. It was done by the calculation of maximum temperature and free electron density in the vicinity of a single gold nanoshell in water during 70 femtosecond single pulse exposure and comparison against published experimental data.

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Yevgeniy R. Davletshin, J. Carl Kumaradas. 2017-05-11. Theoretical analysis of optoporation efficiency and bubble formation during femtosecond pulse interaction with gold nanoshell. https://arxiv.org/abs/1705.03994

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