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arXiv · 1812.02275

Generalizability of predictive models for intensive care unit patients

Alistair E. W. Johnson·Tom J. Pollard·Tristan Naumann
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Abstract

A large volume of research has considered the creation of predictive models for clinical data; however, much existing literature reports results using only a single source of data. In this work, we evaluate the performance of models trained on the publicly-available eICU Collaborative Research Database. We show that cross-validation using many distinct centers provides a reasonable estimate of model performance in new centers. We further show that a single model trained across centers transfers well to distinct hospitals, even compared to a model retrained using hospital-specific data. Our results motivate the use of multi-center datasets for model development and highlight the need for data sharing among hospitals to maximize model performance.

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Alistair E. W. Johnson, Tom J. Pollard, Tristan Naumann. 2018-12-06. Generalizability of predictive models for intensive care unit patients. https://arxiv.org/abs/1812.02275

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