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arXiv · 1907.13434

Optimizing vaccine distribution networks in low and middle-income countries

Yuwen Yang·Hoda Bidkhori·Jayant Rajgopal
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Abstract

Vaccination has been proven to be the most effective method to prevent infectious diseases. However, there are still millions of children in low and middle-income countries who are not covered by routine vaccines and remain at risk. The World Health Organization - Expanded Programme on Immunization (WHO-EPI) was designed to provide universal childhood vaccine access for children across the world and in this work, we address the design of the distribution network for WHO-EPI vaccines. In particular, we formulate the network design problem as a mixed integer program (MIP) and present a new algorithm for typical problems that are too large to be solved using commercial MIP software. We test the algorithm using data derived from four different countries in sub-Saharan Africa and show that the algorithm is able to obtain high-quality solutions for even the largest problems within a few minutes.

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Yuwen Yang, Hoda Bidkhori, Jayant Rajgopal. 2019-07-25. Optimizing vaccine distribution networks in low and middle-income countries. https://doi.org/10.1016/j.omega.2020.102197

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