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arXiv · 1910.14623

Guidelines for reporting single-cell RNA-Seq experiments

Anja Füllgrabe·Nancy George·Matthew Green·Parisa Nejad·Bruce Aronow·Laura Clarke·Silvie Korena Fexova·Clay Fischer·Mallory Ann Freeberg·Laura Huerta·Norman Morrison·Richard H. Scheuermann·Deanne Taylor·Nicole Vasilevsky·Nils Gehlenborg·John Marioni·Sarah Teichmann·Alvis Brazma·Irene Papatheodorou
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Abstract

Single-cell RNA-Sequencing (scRNA-Seq) has undergone major technological advances in recent years, enabling the conception of various organism-level cell atlassing projects. With increasing numbers of datasets being deposited in public archives, there is a need to address the challenges of enabling the reproducibility of such data sets. Here, we describe guidelines for a minimum set of metadata to sufficiently describe scRNA-Seq experiments, ensuring reproducibility of data analyses.

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Anja Füllgrabe, Nancy George, Matthew Green, Parisa Nejad, Bruce Aronow, Laura Clarke, Silvie Korena Fexova, Clay Fischer, Mallory Ann Freeberg, Laura Huerta, Norman Morrison, Richard H. Scheuermann, Deanne Taylor, Nicole Vasilevsky, Nils Gehlenborg, John Marioni, Sarah Teichmann, Alvis Brazma, Irene Papatheodorou. 2019-10-31. Guidelines for reporting single-cell RNA-Seq experiments. https://doi.org/10.1038/s41587-020-00744-z

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