Anatomical Predictions using Subject-Specific Medical Data

Marianne Rakic; John Guttag; Adrian V. Dalca

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arXiv · 2006.00090

Anatomical Predictions using Subject-Specific Medical Data

Marianne Rakic·John Guttag·Adrian V. Dalca

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Abstract

Changes over time in brain anatomy can provide important insight for treatment design or scientific analyses. We present a method that predicts how a brain MRI for an individual will change over time. We model changes using a diffeomorphic deformation field that we predict using function using convolutional neural networks. Given a predicted deformation field, a baseline scan can be warped to give a prediction of the brain scan at a future time. We demonstrate the method using the ADNI cohort, and analyze how performance is affected by model variants and the subject-specific information provided. We show that the model provides good predictions and that external clinical data can improve predictions.

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Marianne Rakic, John Guttag, Adrian V. Dalca. 2020-05-29. Anatomical Predictions using Subject-Specific Medical Data. https://arxiv.org/abs/2006.00090

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