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arXiv · 2011.00219

A mini-review of the diffusion dynamics of DNA-binding proteins: Experiments and models

Seongyu Park·O-chul Lee·Xavier Durang·Jae-Hyung Jeon
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Abstract

In the course of various biological processes, specific DNA-binding proteins must find a particular target sequence/protein or a damaged site on the DNA efficiently. DNA-binding proteins perform this task based on diffusion. Yet, investigations over recent decades have found that the diffusion dynamics of DNA-binding proteins are generally complicated and, further, protein-specific. In this review, we collect the experimental and theoretical studies that quantify the diffusion dynamics of DNA-binding proteins and review them from the viewpoint of diffusion processes.

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Seongyu Park, O-chul Lee, Xavier Durang, Jae-Hyung Jeon. 2020-10-31. A mini-review of the diffusion dynamics of DNA-binding proteins: Experiments and models. https://doi.org/10.1007/s40042-021-00060-y

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