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arXiv · 2103.05125

Theory of cell membrane interaction with glass

Richard W. Clarke
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Abstract

There are three regimes of cell membrane interaction with glass - Tight and loose adhesion, separated by repulsion. Explicitly including hydration, this paper evaluates the pressure between the surfaces as functions of distance for ion-correlation and ion-screened electrostatics, and electromagnetic fluctuations. The results agree with data for tight adhesion energy (0.5-3 vs 0.4-4 mJ/m2), detachment pressure (7.9 vs 9 MPa), and peak repulsion (3.4-7.5 vs 5-10 kPa), also matching the repulsion's distance dependence upon renormalization by steric pressure mainly from undulations.

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Richard W. Clarke. 2021-03-08. Theory of cell membrane interaction with glass. https://doi.org/10.1103/physreve.103.032401

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