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arXiv · 2107.03686

A bayesian reanalysis of the phase III aducanumab (ADU) trial

Tommaso Costa·Franco Cauda
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Abstract

In this article we have conducted a reanalysis of the phase III aducanumab (ADU) summary statistics announced by Biogen, in particular the result of the Clinical Dementia Rating-Sum of Boxes (CDR-SB). The results showed that the evidence on the efficacy of the drug is very low and a more clearer view of the results of clinical trials are presented in the Bayesian framework that can be useful for future development and research in the field.

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Tommaso Costa, Franco Cauda. 2021-07-08. A bayesian reanalysis of the phase III aducanumab (ADU) trial. https://arxiv.org/abs/2107.03686

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