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arXiv · 2108.04933

Optical phased array neural probes for beam-steering in brain tissue

Wesley D. Sacher·Fu-Der Chen·Homeira Moradi-Chameh·Xinyu Liu·Ilan Felts Almog·Thomas Lordello·Michael Chang·Azadeh Naderian·Trevor M. Fowler·Eran Segev·Tianyuan Xue·Sara Mahallati·Taufik A. Valiante·Laurent C. Moreaux·Joyce K. S. Poon·Michael L. Roukes
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Abstract

Implantable silicon neural probes with integrated nanophotonic waveguides can deliver patterned dynamic illumination into brain tissue at depth. Here, we introduce neural probes with integrated optical phased arrays and demonstrate optical beam steering in vitro. Beam formation in brain tissue was simulated and characterized. The probes were used for optogenetic stimulation and calcium imaging.

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Wesley D. Sacher, Fu-Der Chen, Homeira Moradi-Chameh, Xinyu Liu, Ilan Felts Almog, Thomas Lordello, Michael Chang, Azadeh Naderian, Trevor M. Fowler, Eran Segev, Tianyuan Xue, Sara Mahallati, Taufik A. Valiante, Laurent C. Moreaux, Joyce K. S. Poon, Michael L. Roukes. 2021-08-10. Optical phased array neural probes for beam-steering in brain tissue. https://doi.org/10.1364/ol.441609

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