Online Optimization of Stimulation Speed in an Auditory Brain-Computer Interface under Time Constraints

Abstract

The decoding of brain signals recorded via, e.g., an electroencephalogram, using machine learning is key to brain-computer interfaces (BCIs). Stimulation parameters or other experimental settings of the BCI protocol typically are chosen according to the literature. The decoding performance directly depends on the choice of parameters, as they influence the elicited brain signals and optimal parameters are subject-dependent. Thus a fast and automated selection procedure for experimental parameters could greatly improve the usability of BCIs. We evaluate a standalone random search and a combined Bayesian optimization with random search in a closed-loop auditory event-related potential protocol. We aimed at finding the individually best stimulation speed -- also known as stimulus onset asynchrony (SOA) -- that maximizes the classification performance of a regularized linear discriminant analysis. To make the Bayesian optimization feasible under noise and the time pressure posed by an online BCI experiment, we first used offline simulations to initialize and constrain the internal optimization model. Then we evaluated our approach online with 13 healthy subjects. We could show that for 8 out of 13 subjects, the proposed approach using Bayesian optimization succeeded to select the individually optimal SOA out of multiple evaluated SOA values. Our data suggests, however, that subjects were influenced to very different degrees by the SOA parameter. This makes the automatic parameter selection infeasible for subjects where the influence is limited. Our work proposes an approach to exploit the benefits of individualized experimental protocols and evaluated it in an auditory BCI. When applied to other experimental parameters our approach could enhance the usability of BCI for different target groups -- specifically if an individual disease progress may prevent the use of standard parameters.