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arXiv · 2109.13706

Macroscopic current generated by local division and apoptosis in a minimal model of tissue dynamics

Emma Mitchell·Elsen Tjhung
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Abstract

We consider a minimal computational model of tissue dynamics with two active ingredients: local particle division and apoptosis. We neglect other non-equilibrium effects such as self-propulsion. We simulated the steady state dynamics inside an asymmetric channel and we found a net macroscopic current along the channel. Although such macroscopic current in a similar geometry has been detected in swimming bacteria, our results showed that local division and apoptosis are sufficient to generate a macroscopic current, without any need for a self-propulsion/swimming mechanism. Our results might have applications in tissue engineering such as controlling tissue growth via a geometrically non-uniform substrate.

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Emma Mitchell, Elsen Tjhung. 2021-09-28. Macroscopic current generated by local division and apoptosis in a minimal model of tissue dynamics. https://arxiv.org/abs/2109.13706

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