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arXiv · 2110.12238

Enhanced visibility through microbubble-induced photoacoustic fluctuation imaging

Marco A. Inzunza-Ibarra·J. Angel Navarro-Becerra·Venkatalakshmi Narumanchi·Nick Bottenus·Todd W. Murray·Mark A. Borden
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Abstract

A photoacoustic contrast mechanism is presented based on the photoacoustic fluctuations induced by microbubbles flowing inside a micro vessel filled with a continuous absorber. It is demonstrated that the standard deviation of a homogeneous absorber mixed with microbubbles increases non-linearly as the microbubble concentration and microbubble size is increased. This effect is then utilized to perform photoacoustic fluctuation imaging with increased visibility and contrast of a blood flow phantom.

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Marco A. Inzunza-Ibarra, J. Angel Navarro-Becerra, Venkatalakshmi Narumanchi, Nick Bottenus, Todd W. Murray, Mark A. Borden. 2021-10-23. Enhanced visibility through microbubble-induced photoacoustic fluctuation imaging. https://doi.org/10.1121/10.0009129

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