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arXiv · 2111.01282

An immunological autobiography: my year as a COVID-19 vaccine trial participant

Ross M. Kedl
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Abstract

I present here longitudinal evaluation of T and B cell immunity to SARS-CoV2 and variants of concern (VOC) from a single subject (me) over an entire year post vaccination. After enrolling in the Moderna phase III clinical trial, I collected my own biological samples pre- and post-immunization in the event of being a recipient of the experimental vaccine. The evidence strongly supports the conclusion that I did not receive the placebo. The analysis is admittedly limited to an n of 1, but the results fit well with data taken from published works and represent one of the more comprehensive longitudinal evaluations of vaccine-elicited immunity within a single individual yet to be undertaken. Though the data amount to a well-documented anecdote, given its granularity, it is not without its insights and may be of further use in directing future longitudinal studies that have actual statistical significance.

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Ross M. Kedl. 2021-11-01. An immunological autobiography: my year as a COVID-19 vaccine trial participant. https://arxiv.org/abs/2111.01282

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