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arXiv · 2111.13689

A physical perspective to understand myelin. II. The physical origin of myelin development

Yonghong Liu·Yapeng Zhang·Wenji Yue·Ran Zhu·Tianruo Guo·Fenglin Liu·Yubin Huang·Tianzhun Wu·Hao Wang
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Abstract

The physical principle of myelin development is obtained from our previous study by explaining Peter's quadrant mystery: an external applied negative and positive E-field can promote and inhibit the growth of the inner tongue of the myelin sheath, respectively. In this study, this principle is considered as a fundamental hypothesis, named Hypothesis-E, to explain more phenomena about myelin development systematically. Specifically, the g-ratio and the fate of the Schwann cell's differentiation are explained in terms of E-field. Moreover, an experiment is proposed to validate this theory.

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Yonghong Liu, Yapeng Zhang, Wenji Yue, Ran Zhu, Tianruo Guo, Fenglin Liu, Yubin Huang, Tianzhun Wu, Hao Wang. 2021-11-26. A physical perspective to understand myelin. II. The physical origin of myelin development. https://arxiv.org/abs/2111.13689

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