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arXiv · 2205.09271

Stochastic mRNA production by a three-state gene

Boris Rubinstein·Jay Unruh·Julia Zeitlinger
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Abstract

We consider a model of mRNA production governed by the dynamics of a gene that exists in three possible states -- inactive, poised and active. The transitions between the adjacent states are controlled by stochastic processes characterized by corresponding on/off rates. mRNA is produced only when the gene is in active state and we also consider mRNA denaturation leading to its death.

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Boris Rubinstein, Jay Unruh, Julia Zeitlinger. 2022-05-19. Stochastic mRNA production by a three-state gene. https://arxiv.org/abs/2205.09271

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