Autonomous Medical Needle Steering In Vivo

Alan Kuntz; Maxwell Emerson; Tayfun Efe Ertop; Inbar Fried; Mengyu Fu; Janine Hoelscher; Margaret Rox; Jason Akulian; Erin A. Gillaspie; Yueh Z. Lee; Fabien Maldonado; Robert J. Webster III; Ron Alterovitz

arXiv · 2211.02597

Autonomous Medical Needle Steering In Vivo

Alan Kuntz·Maxwell Emerson·Tayfun Efe Ertop·Inbar Fried·Mengyu Fu·Janine Hoelscher·Margaret Rox·Jason Akulian·Erin A. Gillaspie·Yueh Z. Lee·Fabien Maldonado·Robert J. Webster III·Ron Alterovitz

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Abstract

The use of needles to access sites within organs is fundamental to many interventional medical procedures both for diagnosis and treatment. Safe and accurate navigation of a needle through living tissue to an intra-tissue target is currently often challenging or infeasible due to the presence of anatomical obstacles in the tissue, high levels of uncertainty, and natural tissue motion (e.g., due to breathing). Medical robots capable of automating needle-based procedures in vivo have the potential to overcome these challenges and enable an enhanced level of patient care and safety. In this paper, we show the first medical robot that autonomously navigates a needle inside living tissue around anatomical obstacles to an intra-tissue target. Our system leverages an aiming device and a laser-patterned highly flexible steerable needle, a type of needle capable of maneuvering along curvilinear trajectories to avoid obstacles. The autonomous robot accounts for anatomical obstacles and uncertainty in living tissue/needle interaction with replanning and control and accounts for respiratory motion by defining safe insertion time windows during the breathing cycle. We apply the system to lung biopsy, which is critical in the diagnosis of lung cancer, the leading cause of cancer-related death in the United States. We demonstrate successful performance of our system in multiple in vivo porcine studies and also demonstrate that our approach leveraging autonomous needle steering outperforms a standard manual clinical technique for lung nodule access.

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Alan Kuntz, Maxwell Emerson, Tayfun Efe Ertop, Inbar Fried, Mengyu Fu, Janine Hoelscher, Margaret Rox, Jason Akulian, Erin A. Gillaspie, Yueh Z. Lee, Fabien Maldonado, Robert J. Webster III, Ron Alterovitz. 2022-11-04. Autonomous Medical Needle Steering In Vivo. https://arxiv.org/abs/2211.02597

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