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arXiv · 2301.00392

Enzyme-enriched condensates show self-propulsion, positioning, and coexistence

Leonardo Demarchi·Andriy Goychuk·Ivan Maryshev·Erwin Frey
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Abstract

Enzyme-enriched condensates can organize the spatial distribution of their substrates by catalyzing non-equilibrium reactions. Conversely, an inhomogeneous substrate distribution induces enzyme fluxes through substrate-enzyme interactions. We find that condensates move towards the center of a confining domain when this feedback is weak. Above a feedback threshold, they exhibit self-propulsion, leading to oscillatory dynamics. Moreover, catalysis-driven enzyme fluxes can lead to interrupted coarsening, resulting in equidistant condensate positioning, and to condensate division.

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Leonardo Demarchi, Andriy Goychuk, Ivan Maryshev, Erwin Frey. 2023-01-01. Enzyme-enriched condensates show self-propulsion, positioning, and coexistence. https://doi.org/10.1103/physrevlett.130.128401

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