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arXiv · 2302.10599

The construction of ceRNAs network reveals the prognostic characteristics of prostate cancer

Mengjie Chen
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Abstract

The dysregulation of transcripts is characterized as one of the main mechanisms in tumor pathogenesis. The recent discovery developed a new hypothesis, competitive endogenous RNAs (ceRNAs), which could regulate other RNA transcripts via competing for their shared miRNAs. The interaction of elements in ceRNAs network was involved in a large range of biological reactions and facilitate to cancer progression. In this study, we performed a comprehensive investigation on the regulatory mechanisms and functional roles of ceRNAs in prostate cancer (PCa) and constructed a ceRNAs network which could possess potential value in patient prognosis and be evaluated as therapeutic targets for PCa.

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Mengjie Chen. 2023-02-21. The construction of ceRNAs network reveals the prognostic characteristics of prostate cancer. https://arxiv.org/abs/2302.10599

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