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arXiv · 2310.19505

Transmission infrared micro-spectroscopic study of individual human hair

Chen Li·Yuhan Du·Haonan Chen·Xinxin Han·Wenbin Wu·Xiufang Kong·Cheng Zhang·Xiang Yuan
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Abstract

Understanding the optical transmission property of human hair, especially in the infrared regime, is vital in physical, clinical, and biomedical research. However, the majority of infrared spectroscopy on human hair is performed in the reflection mode, which only probes the absorptance of the surface layer. The direct transmission spectrum of individual hair without horizontal cut offers a rapid and non-destructive test of the hair cortex but is less investigated experimentally due to the small size and strong absorption of the hair. In this work, we conduct transmission infrared micro-spectroscopic study on individual human hair. By utilizing direct measurements of the transmission spectrum using a Fourier-transform infrared microscope, the human hair is found to display prominent band filtering behavior. The high spatial resolution of infrared micro-spectroscopy further allows the comparison among different regions of hair. In a case study of adult-onset Still's disease, the corresponding infrared transmission exhibits systematic variations of spectral weight as the disease evolves. The geometry effect of the internal hair structure is further quantified using the finite-element simulation. The results imply that the variation of spectral weight may relate to the disordered microscopic structure variation of the hair cortex during the inflammatory attack. Our work reveals the potential of hair infrared transmission spectrum in tracing the variation of hair cortex retrospectively.

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Chen Li, Yuhan Du, Haonan Chen, Xinxin Han, Wenbin Wu, Xiufang Kong, Cheng Zhang, Xiang Yuan. 2023-10-30. Transmission infrared micro-spectroscopic study of individual human hair. https://doi.org/10.1117/1.jbo.28.11.116501

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