Using recurrent neural networks to predict aspects of 3-D structure of folded copolymer sequences

R. G. Reilly; M. -T. Kechadi; Yu. A. Kuznetsov; E. G. Timoshenko; K. A. Dawson

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arXiv · 2407.11493

Using recurrent neural networks to predict aspects of 3-D structure of folded copolymer sequences

R. G. Reilly·M. -T. Kechadi·Yu. A. Kuznetsov·E. G. Timoshenko·K. A. Dawson

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Abstract

The neural network techniques are developed for artificial sequences based on approximate models of proteins. We only encode the hydrophobicity of the amino acid side chains without attempting to model the secondary structure. We use our approach to obtain a large set of sequences with known 3-D structures for training the neural network. By employing recurrent neural networks we describe a way to augment a neural network to deal with sequences of realistic length and long-distant interactions between the sequence regions.

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R. G. Reilly, M. -T. Kechadi, Yu. A. Kuznetsov, E. G. Timoshenko, K. A. Dawson. 2024-07-16. Using recurrent neural networks to predict aspects of 3-D structure of folded copolymer sequences. https://arxiv.org/abs/2407.11493

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