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arXiv · 2408.01280

Hydrodynamics of molecular rotors in lipid membranes

Vinny C. Suja·Naomi Oppenheimer·Howard A. Stone
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Abstract

Molecular rotors form twisted conformations upon photoexcitation, with their fluorescent relaxation time serving as a measure of viscosity. They have been used to assess membrane viscosities but yield higher values compared to other methods. Here, we show that the rotor's relaxation time is influenced by a combination of membrane viscosity and interleaflet friction. We present a theory for the relaxation time and obtain a correction factor that accounts for the discrepancy. If the membrane's viscosity is known, molecular rotors may enable the extraction of the elusive interleaflet friction.

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Vinny C. Suja, Naomi Oppenheimer, Howard A. Stone. 2024-08-02. Hydrodynamics of molecular rotors in lipid membranes. https://arxiv.org/abs/2408.01280

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