Algorithmical Aspects of Some Bio Inspired Operations

Marius Dumitran

Home/Archive/arXiv

arXiv · 2501.06949

Algorithmical Aspects of Some Bio Inspired Operations

Marius Dumitran

View original source ↗Read source document ↗Export metadata ↓

Abstract

This thesis investigates three biologically inspired operations: prefix-suffix duplication, bounded prefix-suffix duplication, and prefix-suffix-square completion. Duplication, a common genetic mutation, involves repeating DNA sequences and is modeled here as formal operations on words. The prefix-suffix duplication generates non-context-free languages, even from simple initial words. To better reflect biological processes, we propose a bounded variant that limits duplication length, resolving unsolved problems and aligning with biochemical realities. We also introduce the prefix-suffix-square completion operation, which generates squares at sequence ends. This operation enables the generation of infinite words such as Fibonacci, Period-doubling, and Thue-Morse, which contain squares but avoid higher exponent repetitions, highlighting unique structural properties. In contrast, prefix-suffix duplication cannot generate certain infinite words, such as Thue-Morse, but can produce cube-free words. Additionally, we address the detection of gapped repeats and palindromes-structures important in DNA and RNA analysis. These involve repeating or reversed factors flanking a central gap. Previous studies imposed constraints on gap length or arm-gap relationships; we extend this by solving the problem in three novel settings. This work advances theoretical insights into biologically inspired operations and their computational applications in genetic modeling.

Explore related subjects

cs.DS cs.FL

Keep this discovery

BibTeX RIS

Marius Dumitran. 2025-01-12. Algorithmical Aspects of Some Bio Inspired Operations. https://arxiv.org/abs/2501.06949

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related papers

arXiv2026

Quasi-Monte Carlo Beyond Hardy-Krause II: $(1 + \varepsilon)n$ Samples Suffice

Numerical integration studies how well one can estimate the integral of a function $f$ over $[0,1)^d$ using $n$ sample points. The two classical methods, Monte Carlo (MC) and quasi-Monte Carlo (QMC), have complementary strengths and weaknesses, and a fundamental question is to design an approach that combines the benefits of both. Recently, building on the transference principle in discrepancy theory, Bansal and Jiang~\cite{BJ25a} gave a randomized QMC method that bridges MC and QMC guarantees using only i.i.d.\ samples. Their method also goes beyond the classical Koksma--Hlawka inequality: it achieves integration error $\widetilde{O}_d(\sigma_{\mathsf{SO}}(f)/n)$, where the smoothed-out variation $\sigma_{\mathsf{SO}}(f)$ can be substantially smaller than the Hardy--Krause variation that governs the classical bound. However, their algorithm requires $n^2$ i.i.d.\ samples as input, and this quadratic blowup is inherent to any method based on the transference principle. In this work, we bypass the quadratic blowup: for any constant $\varepsilon > 0$, we show that $(1+\varepsilon)n$ i.i.d.\ samples suffice to both obtain the beyond-Hardy--Krause guarantee of~\cite{BJ25a}, resolving an open problem posed there, and to produce low-discrepancy point sequences. Our algorithms are variants of the online Haar-thinning method of Dwivedi, Feldheim, Gurel-Gurevich, and Ramdas~\cite{DFG+19}.

cs.DS↗

arXiv2026

A deterministic $(1+\varepsilon)^n$ approximation for the permanent of a nonnegative matrix

For every fixed $0<\varepsilon\le1$, we give a deterministic strongly polynomial algorithm that, given a nonnegative matrix $A\in\mathbb{R}_{\ge0}^{n\times n}$, returns $Q$ satisfying $\operatorname{per} A\le Q\le(1+\varepsilon)^n\operatorname{per} A$.

cs.DS↗

arXiv2026

Single-Exponential Algorithms and a Polynomial Kernel for Strong Connectivity Augmentation

Strong Connectivity Augmentation (SCA) asks whether a directed acyclic graph can be made strongly connected by adding at most $k$ prescribed links whose total weight is within a given budget. Klinkby, Misra, and Saurabh (SODA 2021) gave an $O^*(2^{O(k\log k)})$-time algorithm and asked whether the problem admits a single-exponential parameterized algorithm and a polynomial kernel. We answer both questions affirmatively: SCA can be solved in $O^*(9^k)$ time and admits a polynomial kernel with $O(k^4)$ vertices and $O(k^{16})$ bits. For unweighted SCA, we obtain $O^*(4^k)$ time and a kernel with $O(k^3)$ vertices. Our algorithms are based on a particularly simple reduction to Strongly Connected Spanning Subgraph with two edge costs.

cs.DS↗