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arXiv · 2503.21539

Experimental and numerical investigation of wavelength and resolution dependency of dynamic optical coherence tomography signals

Shumpei Fujimura·Ibrahim Abd El-Sadek·Rion Morishita·Shuichi Makita·Atsuko Furukawa·Pradipta Mukherjee·Yiheng Lim·Lida Zhu·Yunake Feng·Thitiya Seesan·Satoshi Matsusaka·Yoshiaki Yasuno
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Abstract

The wavelength and system-resolution dependencies of dynamic optical coherence tomography (DOCT) are investigated experimentally and numerically. Experimental investigations demonstrate significant wavelength dependency for the DOCT values but no resolution dependency. Numerical simulations were performed using diffusion, random-ballistic motion, and mono-directional flow-based motion models. Diffusion and random-ballistic motion-based simulations show significant wavelength dependency. Additionally, small but certain resolution dependency was revealed by these simulations. Mono-directional flow simulations did not show wavelength dependency, but did demonstrate resolution dependency. The DOCT value is sensitive to both tissue dynamics and the OCT system specification. These effects should be considered when interpreting DOCT images.

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Shumpei Fujimura, Ibrahim Abd El-Sadek, Rion Morishita, Shuichi Makita, Atsuko Furukawa, Pradipta Mukherjee, Yiheng Lim, Lida Zhu, Yunake Feng, Thitiya Seesan, Satoshi Matsusaka, Yoshiaki Yasuno. 2025-03-27. Experimental and numerical investigation of wavelength and resolution dependency of dynamic optical coherence tomography signals. https://doi.org/10.1364/boe.564030

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