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arXiv · 2505.01206

Design for a Digital Twin in Clinical Patient Care

Anna-Katharina Nitschke·Carlos Brandl·Fabian Egersdörfer·Magdalena Görtz·Markus Hohenfellner·Matthias Weidemüller
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Abstract

Digital Twins hold great potential to personalize clinical patient care, provided the concept is translated to meet specific requirements emerging from established clinical workflows. We present a general and unspecialized Digital Twin design combining knowledge graphs and ensemble learning to reflect the entire patient's clinical journey and assist clinicians in their decision-making. Such a design is predictive, modular, evolving, informed, interpretable and explainable, thus opening broad clinical applications.

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Anna-Katharina Nitschke, Carlos Brandl, Fabian Egersdörfer, Magdalena Görtz, Markus Hohenfellner, Matthias Weidemüller. 2025-05-02. Design for a Digital Twin in Clinical Patient Care. https://doi.org/10.1038/s44401-025-00060-1

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