Bridge2AI: Building A Cross-disciplinary Curriculum Towards AI-Enhanced Biomedical and Clinical Care

John Rincon; Alexander R. Pelletier; Destiny Gilliland; Wei Wang; Ding Wang; Baradwaj S. Sankar; Lori Scott-Sheldon; Samson Gebreab; William Hersh; Parisa Rashidi; Sally Baxter; Wade Schulz; Trey Ideker; Yael Bensoussan; Paul C. Boutros; Alex A. T. Bui; Colin Walsh; Karol E. Watson; Peipei Ping

arXiv · 2505.14757

Bridge2AI: Building A Cross-disciplinary Curriculum Towards AI-Enhanced Biomedical and Clinical Care

John Rincon·Alexander R. Pelletier·Destiny Gilliland·Wei Wang·Ding Wang·Baradwaj S. Sankar·Lori Scott-Sheldon·Samson Gebreab·William Hersh·Parisa Rashidi·Sally Baxter·Wade Schulz·Trey Ideker·Yael Bensoussan·Paul C. Boutros·Alex A. T. Bui·Colin Walsh·Karol E. Watson·Peipei Ping

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Abstract

Objective: As AI becomes increasingly central to healthcare, there is a pressing need for bioinformatics and biomedical training systems that are personalized and adaptable. Materials and Methods: The NIH Bridge2AI Training, Recruitment, and Mentoring (TRM) Working Group developed a cross-disciplinary curriculum grounded in collaborative innovation, ethical data stewardship, and professional development within an adapted Learning Health System (LHS) framework. Results: The curriculum integrates foundational AI modules, real-world projects, and a structured mentee-mentor network spanning Bridge2AI Grand Challenges and the Bridge Center. Guided by six learner personas, the program tailors educational pathways to individual needs while supporting scalability. Discussion: Iterative refinement driven by continuous feedback ensures that content remains responsive to learner progress and emerging trends. Conclusion: With over 30 scholars and 100 mentors engaged across North America, the TRM model demonstrates how adaptive, persona-informed training can build interdisciplinary competencies and foster an integrative, ethically grounded AI education in biomedical contexts.

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John Rincon, Alexander R. Pelletier, Destiny Gilliland, Wei Wang, Ding Wang, Baradwaj S. Sankar, Lori Scott-Sheldon, Samson Gebreab, William Hersh, Parisa Rashidi, Sally Baxter, Wade Schulz, Trey Ideker, Yael Bensoussan, Paul C. Boutros, Alex A. T. Bui, Colin Walsh, Karol E. Watson, Peipei Ping. 2025-05-20. Bridge2AI: Building A Cross-disciplinary Curriculum Towards AI-Enhanced Biomedical and Clinical Care. https://arxiv.org/abs/2505.14757

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